摘要
艾司氯胺酮是一种强效麻醉性镇痛药,目前已用于临床麻醉和术后镇痛中.艾司氯胺酮可通过多种途径给药,有镇痛作用强、起效迅速、消除迅速、不抑制自主呼吸的优点,在小儿麻醉、产科麻醉以及低血容量患者或烧伤患者的麻醉中有一定的优势,且适用于老年患者,在临床中的应用 日益广泛.但艾司氯胺酮的使用剂量、应用方法及联用药物的选择等尚有待进一步探讨.
Abstract
Esketamine is a powerful narcotic analgesic,which has been used in clinical anesthesia and postoperative analgesia.Esketamine can be administered through a variety of ways,with strong analgesic effect,rapid onset,rapid elimination,and no inhibition of spontaneous respiration.It has certain advantages in pediatric anesthesia,obstetric anesthesia,and anesthesia in patients with low blood volume or burn,and is suitable for elderly patients.So esketamine is widely used in clinic.However,the dosage,application method and the choice of combination drugs of esketamine remain to be further discussed.
基金项目
济南市科技创新发展计划(202134068)
山东省自然科学基金面上项目(ZR2020MH391)
济南市"新高校20条"科研带头人工作室项目(202228124)