新型抗精神病药研究进展
Research progress in new antipsychotic drugs
刘鑫 1翟金国1
作者信息
- 1. 济宁医学院精神卫生学院,山东济宁 272067
- 折叠
摘要
近年来发现一些新的药物治疗靶点,为抗精神病药的精准治疗提供了相关依据,推动了新作用机制抗精神病药的研发.微量胺相关受体1激动剂、甘氨酸转运蛋白-1抑制剂、外周限制性毒蕈碱受体拮抗剂、5-羟色胺2A/2C受体反向激动剂等新药的问世,为精神病性症状的治疗提供了新的可能,其因显著的疗效及较轻的不良反应而备受关注.
Abstract
In recent years,many new drug treatment targets have been found,which provided the basis for the precise treatment of antipsychotic drugs and promoted the research and development of new antipsychotic drugs.The development of trace amine-associated receptor 1 agonist,glycine transporter-1 inhibitor,peripherally restricted muscarinic receptor antagonist,5-hydroxytryptamine 2A/2C receptor inverse agonist and other new drugs have provided new possibilities for the treatment of psychotic symptoms and attracted much attention due to their significant efficacy and mild adverse reactions.
关键词
抗精神病药/临床试验/药理作用机制/药物不良反应Key words
antipsychotic agents/clinical trial/pharmacological mechanisms of action/adverse drug reactions引用本文复制引用
出版年
2024
NETL
NSTL
万方数据