Research progress of CD34+cell transplantation for chronic heart failure
CD34+cells have microcirculatory regenerative potential and paracrine anti-inflammatory effects,but the number and function of CD34+cells involved in vascular repair are decreased in patients with heart failure.Multiple trials have found that CD34+cell transplantation therapy in patients with chronic heart failure can improve myocardial performance,reduce neurohumoral activation,improve exercise capacity and quality of life,and even improve the survival rate in patients with heart failure.CD34+cell transplantation may be a future treatment option for patients with chronic heart failure.
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