Eravacycline is a new class of fully synthetic fluortetracycline antibiotics with broad-spectrum antibacterial activity.The existing clinical trials have shown that eravacycline has good efficacy and safety in the treatment of various complex infections,especially in the application of multi-drug resistant bacteria.In this paper,the chemical structure,mechanism of action,antibacterial spectrum,pharmacokinetics/pharmacodynamics,clinical application,and drug resistance of eravacycline were reviewed in order to provide basis and reference for clinical drug use.
关键词
依拉环素/药理作用机制/临床研究/抗药性,细菌
Key words
eravacycline/pharmacological mechanism of action/clinical study/drug resistance,bacterial
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