首页|Separating Kanamycin A And B From The Fermentation Broth

Separating Kanamycin A And B From The Fermentation Broth

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A method to separate Kanamycin A and B from their fermentation broth is proposed in this paper. In order to seek Kanamycin B-sensitive resin, the equilibrium constants of Kanamycin B were estimated by potentiometric titration, and then the resins for test were evaluted by static and dynamicabsorption. The results indicated that the D4 with larger mesh has higher adsorption rate of Kanamycin B and lower adsorption amount of impurity. Using D4 as first column and 732# as late binding columns, the purity of Kanamycin A is higher than 99.0%.

Kanamycin equilibrium constants resins

LI Zhongqin、Xuefengchun、Xu Xiaoping、Guo Yanghao

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Department of Chemical Engineer, Fuzhou University 350002

2004

中国新医药
中华医学健康学会

中国新医药

ISSN：1726-9393
年,卷(期)：2004.3(4)
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