宫腔镜手术在妊娠滋养细胞肿瘤患者鉴别诊断中的应用研究
Study of hysteroscopy apply to differential diagnosis in gestational trophoblastic neoplasia patients
顾宇 1冯凤芝 1向阳 1万希润 1任彤 1杨隽钧1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院妇产科，北京100730
- 折叠
摘要
目的 探讨宫腔镜手术对于妊娠滋养细胞肿瘤( gestational trophoblastic neoplasia,GTN)鉴别诊断的价值以及对其预后的影响。方法 回顾分析本院2005年1月至2013年12月收治的怀疑GTN而行宫腔镜手术的患者的临床资料。结果 47例患者中有4例为GTN。 GTN患者组与非GTN患者组之间的大部分临床资料差异无显著性。所有患者最终均获治愈。结论 根据患者的临床资料难以鉴别GTN时,宫腔镜手术可协助明确诊断,对GTN患者预后无明显影响,并且可以对非GTN疾病进行有效的治疗。
Abstract
Objective To determine the efficacy of hysteroscopy in differential diagnosis of suspected gestational trophoblastic neoplasia ( GTN) patients, and the impact of hysteroscopy on the prognosis of GTN. Method From January 2005 to December 2013, 47 patients with a suspected diagnosis of GTN were admitted to Peking Union Medical College Hospital and underwent hysteroscopy. The clinical data and outcome of these patients were retro-spectively reviewed. Result Totally 47 eligible patients were included. Among these patients, 4 cases were diag-nosed with GTN. There was no statistical difference in the most of the clinical data between GTN patients and non-GTN patients. All the GTN patients achieved complete remission by subsequent chemotherapy or surgical therapy, and all the non-GTN patients were cured by hysteroscopy. Conclusion Hysteroscopy is an effective alternative of di-agnosis for differentiation of GTN from non-GTN diseases, when it was difficult to differentiate GTN from non-GTN diseases by clinical data. Furthermore, it can offer therapeutic treatment for non-GTN diseases.
关键词
宫腔镜手术/妊娠滋养细胞肿瘤/鉴别诊断/疑似/回顾分析Key words
Hysteroscopy/Gestational trophoblastic neoplasm/Antidiastole/Suspected/Retrospective analysis引用本文复制引用
基金项目
北京市科学技术委员会(Z131107002213173)
出版年
2015
NETL
NSTL
维普
万方数据