Risk factors for in-hospital mortality in patients with acute myocardial infarction complicated by gastrointestinal bleeding
Objective To explore risk factors for in-hospital mortality in patients with acute myocardial infarction(AMI)complicated by gastrointestinal bleeding(GIB).Method Patients diagnosed with AMI complicated by GIB between January 2012 and April 2023 at Beijing Anzhen Hospital,Capital Medical University were retrospectively enrolled,of which 53 patients who died during hospitalization were included in the death group,and 223 patients who survived were in the survival group.Univariate analysis and multivariable logistic regression were used to identify risk factors for in-hospital mortality in patients with AMI complicated by GIB.Result Univariate analysis showed that the proportion of patients with high Killip classification,new arrhythmias and mechanical complications,heart rate,levels of leukocytes,blood urea nitrogen(BUN)and creatinine of patients in the death group were higher than those in the survival group on admission,while the systolic blood pressure and left ventricular ejection fraction were lower than those in the survival group,with statistical significance(P＜0.05).In addition,the death group received more transfusions during hospitalization,and the difference was statistically significant(P＜0.01).Multivariate logistic analysis showed that new-onset arrhythmia(OR=2.673,95％CI 1.267-5.636),heart rate＞100 beats/min(OR=3.765,95％CI 1.448-9.790),BUN levels(OR=1.118,95％CI 1.013-1.234),blood transfusion(OR=2.451,95％CI 1.109-5.421)independently associated with in-hospital mortality in patients with AMI complicated by GIB.Conclusion New-onset arrhythmia,heart rate＞100 beats/min,BUN levels,and blood transfusion were risk factors for in-hospital mortality in patients with AMI complicated by GIB.
万方数据
维普
