Application analysis of echocardiography monitoring the effect of remimazolam besylate on cardiac structure and function in mechanically ventilated patients in ICU
Objective To discuss the clinical application value of echocardiography in monitoring the use of remimazolam besylate sedative drugs in ICU mechanically ventilated patients.Method 106 ICU mechanical ventilation patients admitted to Hebei PetroChina Central Hospital from January 2022 to December 2022 were selected and randomly divided into the observation group(using remimazolam besylate for sedation)53 cases and the control group(using non remimazolam besylate for sedation)53 cases.The two-dimensional speckle tracking imagine(2D-STI)parameters,two-dimensional strain parameters and the real-time three dimentional echocardiography(RT-3DE)functional parameters of two groups of ICU mechanically ventilated patients recorded and analyzed.Result There were no significant differences in gender,age,body mass index,American College of Anesthesiologists classification,whether diabetes mellitus was combined,whether hypertension was combined,whether coronary heart disease was combined,whether hyperlipidemia was combined,and etiology between the two groups(P＞0.05).The LVEDD,RV-FAC,TAPSE,E,e,s and e/a in the observation group were significantly higher than those in the control group,RV-Tei was significantly lower than that of control group,with statistical significance(P＜0.05).There were no significant differences in LVEF,RVEDD,a and E/e between 2 groups(P＞0.05).RV-GLS,GLSRs and GLSRa in observation group was significantly lower than that of control group,while the GLSRe was significantly higher than that of control group,with statistical significance(P＜0.05).Anterior and posterior diameter of left atrium,anterior and posterior diameter of left atrium,anterior and posterior diameter of left atrium,LAVmax and LAVmin in observation group were significantly lower than control group,LAEF,LAAEF,LAPFI and LAPEI were significantly higher than control group,with statistical significance(P＜0.05).There was no significant difference in LAPEF,LAST and LAVP between 2 groups(P＞0.05).Conclusion Echocardiography can effectively evaluate the changes in cardiac structure and function during sedative drug use in ICU mechanical ventilation patients,indicating that remimazolam besylate has less damage to the patient's cardiac structure and function,and can reduce the risk of atrial fibrillation.It has important application value for monitoring the condition and clinical treatment of ICU mechanical ventilation patients.
万方数据
维普
