Analysis of clinical characteristics of colorectal polyps in children
Objective To investigate the clinical characteristics of colorectal polyps in children and the effectiveness and safety of endoscopic polypectomy.Method The clinical and endoscopic characteristics of children with colorectal polyps from January 2018 to December 2022 were retrospectively analyzed.Further divide the children into infant group(＜3 years old),preschool group(3-6 years old),and school-age group(＞6 years old)according to their age,and compare the clinical data of children of different ages.Result Among the 278 children,there were 168 males and 110 females.The age range was from 10 months to 15 years old,with an average of(4.7±3.0)years old.There were 70 cases in the infant group,144 cases in the preschool group,and 64 cases in the school-age group.Hematochezia was the main symptom(261 cases,93.9%),and other symptoms included recurrent abdominal pain(29 cases,10.4%)and diarrhea(4 cases,1.4%).68 cases(24.5%,68/278)of pediatric patients showed changes in colitis under endoscopy.4 cases of concurrent anemia,1 case of severe anemia,1 case of moderate anemia,2 cases of mild anemia.And 3 cases of concurrent intussusception.There were 264 cases(95.0%)of single polyp,3 cases of 2 polyps and 11 cases of 3 or more polyps.119 cases were located in the rectum,101 cases in the sigmoid,20 cases in the descending colon,25 cases in the transverse colon,3 cases in the ascending colon,and 10 cases in the more than 2 intestinal segments.Pathological analysis showed that 266 cases were juvenile polyps,3 were adenomatous polyps,8 were inflammatory polyps,and 1 was hyperplastic polyp.Heterozygous mutations of STK11 were detected in 3 of 5 patients with JPS,and STK11 exon 1-9 heterozygous deletions were detected in the other 2 patients.1 case of FAP showed truncated mutation of APC gene.The main endoscopic resection methods were snare polypectomy and EMR.Complications occurred in 11 cases,including bleeding in 5 cases and abdominal pain in 6 cases,all of which were cured after treatment,and no serious complications such as digestive tract perforation was found.The male children in the school-age group had the highest proportion of polyps located in multiple intestinal segments and multiple polyps.The preschool group had the highest incidence of abdominal pain,while the infant group had the highest incidence of rectal bleeding and colitis changes observed under endoscopy,with statistical significance(P＜0.05).Conclusion Colorectal polyps were most common in preschool children,while most of them were juvenile polyps.Colonoscopy was safe and effective for the diagnosis and treatment of intestinal polyp.
万方数据
维普
