Application of oxycodone combined with remimazolam under monitored anesthesia care in unilateral biportal endoscopy
Objective To evaluate the effect of oxycodone combined with remimazolam under monitored anesthesia care(MAC)in unilateral biportal endoscopy(UBE).Method 68 patients with lumbar spinal stenosis who underwent UBE in Chuiyangliu Hospital Affiliated to Tsinghua University from June 2022 to May 2023 were selected as the study objects.They were divided into control group(given sufentanil combined with remimazolam)and the observation group(given oxycodone combined with remimazolam)by the random number table,with 34 patients in each group.The vital signs indexes[mean arterial pressure(MAP),heart rate(HR),respiratory rate(RR),pulse oxygen saturation(SpO2)]and bispectral index(BIS)of the two groups were compared after entering the operating room(T0),after prone position(T1),at the beginning of surgery(T2),at the end of spinal canal decompression(T3),and at the end of surgery(T4).The recovery time and satisfaction scores of the two groups were compared.The incidence of intraoperative adverse reactions was compared between the two groups.Result At T0,T1,T2,T3,T4,there were no significant differences in MAP,HR and BIS between the two groups(P＞0.05).At T2 and T3,RR in observation group was higher than that in control group,and the difference was statistically significant(P＜0.05).At T2,SpO2 in observation group was higher than that in control group,and the difference was statistically significant(P＜0.05).There were no significant differences in recovery time,MOAA/S score,VAS score and surgical satisfaction score between the two groups(P＞0.05).The satisfaction score of patients in observation group was higher than that in control group,and the incidence of respiratory depression was lower than that in control group,and the differences were statistically significant(P＜0.05).Conclusion Oxycodone combined with remimazolam under MAC can improve the vital signs,and improve satisfaction score of patients,and significantly reduce the incidence of respiratory depression of patients in UBE.
OxycodoneRemimazolamUnilateral biportal endoscopyMonitored anesthesia care
万方数据
维普
