Curative effect of panretinal photocoagulation combined with intravitreal injection of conbercept in the treatment of secondary glaucoma caused by ischemic central retinal vein occlusion
Objective To evaluate the effect of the treatment which combined panretinal photocoagulation with intravitreous injection of Conbercept.This treatment is to treat the neovascular glaucoma caused by ischemic central retinal vein occlusion.Method From January,2016 to June,2022,41 patients with neovascular glaucoma caused by ischemic central retinal vein occlusion received the treatment.These patients aging from 55 to 77(60.9±11.2).Before and after the treatment these patients'best corrected visual acuity(BCVA),intraocular pressure(Iop),iris neovascularization and central macular thickness were observed.Result Before and one month after the treatment,there was no statistical difference(t=-1.500,P＞0.05)in visual acuity.After the treatment,irises of 41 patients and neovascularization withered to a varying extent.Before the treatment the value of the Iop was(34.6±4.9)mmHg.The value of the Iop was(28.3±5.8)mmHg one week after the treatment.The value of the Iop was(24.9±4.0)mmHg one month after the treatment.Three months after the treatment the value became(23.6±3.4)mmHg.Before and after the treatment there was statistical difference(P＜0.05).One week after the treatment the value of the central macular thickness is much lower than the value before the treatment,which showed a statistical difference(P＜0.05).Compared to the value before treatment,the value of the central macular thickness one month after the treatment showed no statistical difference(P＞0.05).Conclusion The treatment combining panretinal photocoagulation with intravitreous injection of Conbercept can reduce the intraocular pressure,and control the disease progression of neovascular glaucoma which is caused by ischemic central retinal vein occlusion,meanwhile the macular edema can be reduced.
Ischemic central retinal vein occlusionPanretinal photocoagulationConberceptNeovascular glaucoma
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