Comparison of endoscopic Ivor-Lewis gastric ionization optimization strategy with classical full-endoscopic Ivor-Lewis in the treatment of early and middle stage esophageal cancer
Objective To investigate the effect of endoscopic Ivor-Lewis gastric ionization optimization strategy in the treatment of early and middle stage esophageal cancer.Method Using the principle of simple randomization,82 patients with early and middle stage esophageal cancer treated in Air Force Medical University Tangdu Hospital during 2021.01 to 2023.01 were divided into two groups with 41 cases each.The control group was treated with classical Ivor-Lewis surgery,and the observation group was treated with Ivor-Lewis gastric dissociation optimization strategy.Compare the general conditions of operation,progress of gastrointestinal function recovery,time of getting out of bed of the two groups,as well as gastrointestinal hormones[motilin,gastrin,somatostatin,cholecystokinin(CCK)],stress indexes[ACTH,cortisol(Cor),malonaldehyde(MDA),superoxide dismutase(SOD)],complications and survival rate,recurrence rate before and after surgery.Result The operation time of the observation group was shorter than that of the control group,and the intraoperative blood loss was less than that of the control group(P＜0.05).The recovery time of bowel sound,first exhaust time,first defecation time and oral feeding time in the observation group were earlier than those in the control group(P＜0.05).Serum levels of motilin,gastrin and CCK in the observation group were higher than those in the control group(P＜0.05)at 1 and 3 days after operation.The levels of ACTH,Cor and MDA in the observation group were lower than those in the control group,SOD level was higher than that in control group(P＜0.05).There was no significant difference between the incidence of postoperative complications,recurrence rate and survival rate in the observation group and control group(P＞0.05).Conclusion Endoscopic Ivor-Lewis gastric dissociation optimization strategy can regulate gastrointestinal hormones,improve stress indexes,shorten operation time,reduce blood loss,and promote rapid recovery of gastrointestinal function in patients with early and middle stage esophageal cancer.
Early and middle stage esophageal cancerGastrointestinal hormonesStress indexTotal endoscope Ivor-Lewis surgery
万方数据
维普
