首页|轻中度颅脑损伤致头面部大面积组织缺损游离皮瓣修复术后皮瓣血栓形成危险因素分析

轻中度颅脑损伤致头面部大面积组织缺损游离皮瓣修复术后皮瓣血栓形成危险因素分析

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目的 分析轻中度颅脑损伤所致头面部大面积组织缺损患者行游离皮瓣移植修复术后,皮瓣血栓形成的危险因素.方法 回顾性分析 2020 年 1 月至 2023 年 10 月,在我院接受游离皮瓣移植修复轻中度颅脑损伤所致头面部大面积组织缺损患者临床资料,根据皮瓣修复术后是否发生皮瓣血栓,将研究对象分为无血栓组和血栓组,运用多因素Logistic回归分析法,分析其血栓形成危险因素.结果 共收集到 105 例患者,皮瓣修复术后发生皮瓣血栓 21 例(血栓组),发生率为 20%,其中动脉血栓 8 例(38.09%),静脉血栓 10 例(47.62%),混合血栓 3 例(14.29%).单因素分析结果显示,不同年龄、是否合并糖尿病、术前空腹血糖水平、术前术后血压水平、D-二聚体水平、术后是否给予抗凝药物应用、是否加压包扎是皮瓣血栓形成的相关因素.多因素Logistic回归分析结果显示,术前空腹血糖偏高、术后血压水平偏低、D-二聚体水平较高、术后进行加压包扎是轻中度颅脑损伤所致头面部大面积组织缺损患者行游离皮瓣移植修复术后发生皮瓣血栓的危险因素.结论 轻中度颅脑损伤所致头面部大面积组织缺损患者行游离皮瓣移植修复术后皮瓣血栓形成发生率较高,术前空腹血糖偏高、术后血压水平偏低、D-二聚体水平较高、术后进行加压包扎是其危险因素,临床应重视其风险评估,尽早采取干预措施,以降低血栓形成风险,提升皮瓣存活率.
Analysis of risk factors for skin flap thrombosis after free flap repair of large tissue defects in the head and face caused by mild to moderate traumatic brain injury
Objective Analyze the risk factors for skin flap thrombosis in patients with extensive tissue defects in the head and face caused by mild to moderate traumatic brain injury after undergoing free flap transplantation repair surgery.Methods:Retrospective analysis of clinical data of patients who underwent free skin flap transplantation to repair large tissue defects in the head and face caused by mild to moderate traumatic brain injury in our hospital from January 2020 to October 2023.Based on the occurrence of skin flap thrombosis after skin flap repair surgery,the study subjects were divided into non thrombotic group and thrombotic group.Multivariate logistic regression analysis was used to analyze the risk factors for thrombosis formation.Results:A total of 105 patients were collected,and 21 cases(thrombus group)developed skin flap thrombosis after flap repair surgery,with an incidence rate of 20%.Among them,8 cases(38.09%)had arterial thrombosis,10 cases(47.62%)had venous thrombosis,and 3 cases(14.29%)had mixed thrombosis.The results of univariate analysis showed that different age,whether diabetes was combined,preoperative fasting blood glucose level,preoperative and postoperative blood pressure level,D-dimer level,whether anticoagulant drugs were given after surgery,and whether pressure bandage was the related factors of flap thrombosis.The results of multivariate logistic regression analysis showed that high preoperative fasting blood glucose,low postoperative blood pressure,high D-dimer levels,and postoperative pressure bandaging were risk factors for skin flap thrombosis in patients with large tissue defects in the head and face caused by mild to moderate traumatic brain injury who underwent free flap transplantation repair surgery.Conclusion:The incidence of skin flap thrombosis is higher in patients with extensive tissue defects in the head and face caused by mild to moderate traumatic brain injury after free skin flap transplantation repair.High preoperative fasting blood glucose,low postoperative blood pressure levels,high D-dimer levels,and postoperative pressure bandaging are risk factors.Clinical attention should be paid to risk assessment and early intervention measures should be taken to reduce the risk of thrombosis and improve skin flap survival.

Craniocerebral injuryHead and faceLarge area tissue defectFree skin flapSkin flap transplantation repairThrombosis

宋敬畏、石珂

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南阳市中心医院,河南 南阳,473000

颅脑损伤 头面部 大面积组织缺损 游离皮瓣 皮瓣移植修复 血栓形成

2024

中国医疗美容
中国整形美容协会

中国医疗美容

影响因子:0.454
ISSN:2095-0721
年,卷(期):2024.14(2)
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