Constructing a predictive model for moderate to severe Vaginal Laxity syndrome based on pelvic floor pressure assessment
Objective To explore the risk factors for moderate to severe vaginal laxity syndrome(VLS)and build a prediction model.Methods The pelvic floor pressure assessment data of patients in the pelvic floor reconstruction outpatient and inpatient departments of the Third Affiliated Hospital of Zhengzhou University from May 2021 to May 2023 were collected(a total of 948 cases),and univariate analysis and logistic regression were used to analyze the occurrence of moderate to severe cases.Factors affecting vaginal laxity,a prediction model for moderate to severe VLS was constructed and internally verified.In addition,data from June to August 2023(143 cases in total)were collected for external verification.Results Moderate and severe vaginal relaxation syndrome occurred in 534 cases.Among them,women with age(OR=0.951,95%CI;0.935～0.967,P<0.001)and women with one or more vaginal births(OR=7.419,95%CI:4.719～11.692,P<0.001;OR=12.329,95%CI:7.324～20.754,P<0.001),women with one or more cesarean deliveries(OR=1.697,95%CI:1.083～2.659,P=0.021;OR=3.136,95%CI:1.738～5.659,P<0.001),POP(OR=2.845,95%CI:2.0 29～3.987,P<0.001),hysterectomy(OR=0.094,95%CI:0.025～0.352,P<0.001);the average value of the post-resting phase(OR=1.135,95%CI;1.085～1.219,P=0.002)is related to whether moderate to severe VLS occurs.Based on the above factors,a risk prediction model for moderate or above VLS was constructed,and the modeling team was internally verified The corrected C index is 0.729,and the C index of the ROC curves of the modeled group and the modeled group are 0.788 and 0.807 respectively.DCA curve analysis of the two groups shows that the model has a threshold probability of 20%to 90%in the modeling group and benefits from 40%to 100%in the validation group,suggesting that the model has good discrimination and consistency.It has good clinical value.Conclusion The risk prediction model for moderate and severe VLS constructed in this study can guide clinical practice to a certain extent,provide patients with corresponding diagnosis and treatment suggestions,and provide theoretical support for the prevention of VLS.
Vaginal Laxity syndromePelvic organ prolapsealignment chartprediction modelverification
万方数据
维普
