Research progress on the pathological mechanism and treatment of keloids
Scar is a common skin lesion caused by surgical incisions,wounds,burns,and other skin lesions that damage the dermis reticular layer.From a pathological perspective,it can be divided into two categories:physiological scars and pathological scars.Physiological scars refer to the normal healing response after skin injury,without obvious discomfort,affecting normal life,and requiring no treatment;Pathological scars mainly include hypertrophic scars and keloids[1].Keloids in pathological scars are considered a benign tumor of the skin,accompanied by excessive proliferation of scar fibroblasts.Their formation mechanism is complex,the cure rate is low,and they are prone to recurrence.They are considered a difficult disease,and their treatment remains a challenge.This paper will provide a review of the pathological mechanisms and treatment research progress of scar formation,especially keloids.
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