Effects of L-vitamin C iontophotosis and vitamin E combined with Q-switch 1064nm laser on MASI scores in patients with melasma
Objective To investigate the effects of L-vitamin C iontophotosis and vitamin E combined with Q-switch 1064nm laser on patients'melasma lesion severity(MASI)score.Methods A total of 122 patients who received melasma treatment in our hospital from January 2022 to January 2023 were randomly divided into CQ group and CQE group with 61 patients in each group.The CQ group was treated with levovitamin C iontophoto and Q-switch 1064nm laser,and the CQE group was treated with levovitamin C iontophoto and vitamin E orally and externally combined with Q-switch 1064nm laser.Both groups were treated for 6 months.The clinical efficacy of the two groups after treatment was evaluated.MASI scores were compared before treatment and 1,2,3 and 6 months after treatment,respectively,and the quality of life of patients before treatment and 3 and 6 months after treatment were observed[MELASQOL].Results After 6 months of treatment,the total effective rate of CQE group was significantly higher than that of CQ group(P<0.05).The MASI score and MELASQOL score after 1,2,3 and 6 months of treatment in both groups were significantly lower than those before treatment(P<0.05),and the two scores in CQE group were significantly lower than those in CQ group at each time point(P<0.05).Conclusion L-vitamin C iontophil and Q-switch 1064nm laser therapy combined with vitamin E internal and external application in the treatment of melasma has good clinical therapeutic effect,which can help repair skin lesions and significantly improve the quality of life,and is worthy of clinical promotion.
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