Clinical observation of 1565nm non-ablative fractional laser combined with salicylic acid in treatment of refractory melasma
Objective To investigate the clinical effect of 1565nm non-ablative fractional laser combined with salicylic acid in the treatment of refractory melasma.Methods A total of 80 patients with refractory melasma treated in our hospital from February 2022 to March 2024 were selected and divided into experimental group and control group according to different treatment methods,with 40 cases in each group.The control group was treated with 1565nm non-ablative fractional laser,and the experimental group was treated with salicylic acid on the basis of the control group,and the effects of the two groups were compared.Results The total effective rate of experimental group(97.50%)was significantly higher than that of control group(80.00%)(X²=4.507,P=0.034).The improvement of skin area,DLQI score and skin color of refractory melasma patients in experimental group was significantly better than that in control group(P<0.05),and the incidence of adverse reactions was not significantly different(P>0.05).Conclusion 1565nm non-ablative fractional laser combined with salicylic acid has a good clinical effect on refractory melasma.
万方数据
维普
