Clinical Observation of Recombinant Human Basic Fibroblast Growth Factor Assisted Pulsed Dye Laser Treatment for Rosacea
Objective Analysis of the clinical efficacy of recombinant human basic fibroblast growth factor assisted pulsed dye laser treatment for rosacea.Methods The research subjects were patients with rosacea admitted to General Hospital of China Aviation from November 2022 to October 2023.Randomly select 40 patients from the patient population treated with pure dye laser and include them in the control group.Forty patients were randomly selected from the patient population treated with dye laser combined with growth factor and included in the observation group.Compare the symptom scores and skin barrier function indicators of rosacea before and after treatment between two groups of patients Acne QOL score.Compare the clinical outcomes of patients after treatment.Results Before treatment,two groups of patients had rosacea symptom scores,skin barrier function indicators There was no statistically significant difference in Acne QOL scores and other comparisons.After treatment,the symptom score of rosacea in the observation group was lower than that in the control group(P＜0.05),TEWL is lower than the control group,and the moisture content of the stratum comeum is lower The EI was higher than that of the control group(P＜0.05).The Acne QOL score of the observation group was(96.45±18.47),and there was no statistically significant difference compared to the control group(82.49±16.53)score(t=3.56,P=0.001).The clinical effect of the observation group was better than that of the control group,and the difference was statistically significant(approximate chi square x2=4.15,P=0.04).Conclusion Rh-bFGF significantly improves the clinical efficacy of pulsed dye laser treatment for rosacea,repairs the skin barrier function of rosacea patients,and is worthy of further clinical research and promotion.
rosaceapulse dye laser,595nmrecombinant human alkaline fibroblast growth factorskin barrier functionsymptom scorescne QOL score
万方数据
维普
