Efficacy observation of Banxia Xiexin decoction combined with Siwei Huanglian Lotion in Treatment of Mild and Moderate Acne Rosacea with Syndrome of Spleen-Stomach Damp-Heat
Objective To analyze the effect of Banxia Xiexin decoction plus Siwei Huanglian lotion in treatment of mild and moderate acne rosacea(AR)with syndrome of spleen-stomach damp-heat.Methods A total of 98 cases of mild to moderate AR admitted to Nantong Tongzhou District hospital of traditional Chinese medicine from April of 2021 to April of 2023 were screened and divided into control group and treatment group according to different treatment method with 49 cases in each group.Control group was given with minocycline hydrochloride capsule with 50 mg twice a day.Based on the control group,the treatment group were treated with conventional drugs and Banxia Xiexin Decoction combined with Siwei Huanglian lotion.Both groups were observed continuously for 4 months.The skin lesion score,therapeutic effect and skin physiological index were compared between the two groups of mild to moderate AR cases.Results After 4 months of treatment,the scores of erythema,telangiectasia,papules and pustules of AR cases in two groups were decreased,and the scores of above indexes of AR cases for treatment group were evidently lower(P<0.05).After 4 months'treatment,total effective rate for AR cases for treatment group(93.88%)was evidently higher than control group(77.55%)(P<0.05).After 4 months of treatment,the erythema index,transcutaneous water loss,skin oil were reduced,and the water content of stratum comeum was increased in two groups of AR cases,and the improvement of the above indicators for treatment group was better than control group(P<0.05).Conclusion The efficacy of Banxia Xiexin decoction combined with Siwei Huanglian lotion in treatment of mild and moderate AR cases with syndrome of spleen-stomach damp-heat is evident,can effectively improve the patient's skin lesion symptoms,and promote the further improvement of skin physiological function.
Acne RosaceaBanxia Xiexin DecoctionSiwei Huanglian LotionEfficacySyndrome of Spleen-Stomach Damp-Heat