Observation of curative effect of fractional CO2 laser combined with topical triamcinolone and fluorouracil in the treatment of hypertrophic scars
Objective To evaluate the clinical efficacy and security of superpulsed carbon dioxide laser combined with topical triamcinolone and fluorouracil in the treatment of hypertrophic scars.Methods A total of 80 patients with hypertrophic scar admitted to Sanming First Hospital Affiliated to Fujian Medical University from January 2021 to January 2023 were selected and divided into two groups according to different treatments,40 cases in each group.The control group was treated with simple laser treatment,and the experimental group was treated with laser combined with triamcinolone acetonide and fluorouracil mixture immediately after surgery.The two groups of patients were treated once a month,with an interval of 1 month,and received a total of 8 treatments.The Vancouver Scar Assessment Scale(VSS)score and patient scar assessment scale(PSAs)score were compared between the two groups before treatment,2 months,4 months,6 months and 8 months after treatment.The dermatological quality of life index(DLQI)scores were performed before treatment,4 months and 8 months after treatment in the two groups.Results Both groups of patients completed all treatments.With the increase of treatment times,the VSS score and PSAs score of both groups gradually decreased.The VSS score and PSAs score of the experimental group were lower than those of the control group,and the difference was statistically significant(P＜0.05).The DLQI score of the experimental group was lower than that of the control group,and the difference was statistically significant(P＜0.05).Conclusions The combination of superpulse carbon dioxide laser with external triamcinolone and fluorouracil has better curative effect and higher safety,which is worthy of clinical promotion.
万方数据
维普
