Research progress on biphasic calcium phosphate for bone tissue engineering
Maxillofacial bone defects caused by accidents,diseases,or aging have serious adverse effects on the lives and health of patients,putting enormous pressure on the social healthcare system.In clinical practice,autogenous bone transplantation or bone substitute transplantation is mainly used to promote the regeneration of bone defects.Autologous bone transplantation has many limitations,and bone substitute transplantation has always been a hot topic of concern in the medical community.Among various bone substitute materials,biphasic calcium phosphate(BCP)has good biocompatibility,bone guidance,and adjustable degradation rate,and has shown initial effectiveness as a bone substitute material for repairing tissue defects.This article discusses the following aspects of BCP:the composition and physicochemical characteristics of BCP;Preparation method of BCP;The application progress of BCP in the field of bone tissue engineering.