To Investigate the Relationship Between Brain MRI Imaging and Symptoms and Its Clinical Significance in Patients with First Episode Schizophrenia
Objective:To explore and analyze the relationship between craniocerebral MRI imaging and symptoms in patients with first-episode schizophrenia and its clinical significance.Methods:56 cases of first-episode schizophrenia patients admitted to our hospital from February 2020 to April 2022 were selected as the observation group,and 50 cases of healthy people admitted to our hospital for physical examination during the same period were selected as the control group.Brain MRI imaging examinations were performed in both groups,and imaging examination indexes of patients in the two groups were compared.The Positive and Negative Symptom Scale(PANSS)was used to evaluate the severity of patients'symptoms.Pearson test was used to analyze and explore the correlation between imaging indicators and clinical symptoms in patients with first-episode schizophrenia.Results:Compared with the control group,the observation group had higher vertical distance between the left and right sides of the corpus callosum and below the fornix,the horizontal distance between the corpus callosum and below the fornix and the ventricle area,and the difference was statistically significant(P<0.05).Pearson correlation analysis showed that there was a significant positive correlation between the left proximal corpus callosum dome distance and negative symptom score(P<0.05).Conclusion:The left and right brains show obvious asymmetry in patients with the first episode of schizophrenia,and the height close to the corpus callosum is significantly higher than that of normal people,and the imaging index can show a significant positive correlation with the negative symptoms of the first schizophrenia.
first episode schizophreniacraniocerebral MRIimaging indexnegative symptomscorrelation