首页|探讨罗式全自动电化学发光分析仪检测血清AFP、CEA在诊断肝癌中的应用

探讨罗式全自动电化学发光分析仪检测血清AFP、CEA在诊断肝癌中的应用

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目的:探究与分析罗式全自动电化学发光分析仪检测血清甲胎蛋白(AFP)、癌胚抗原(CEA)在诊断肝癌中的应用.方法:选取自2018年7月~2022年7月本院收治的89例肝癌患者作为观察组,并选择同期收治的80例健康成年人作为对照组,采用罗式全自动电化学发光分析仪对两组人员血清AFP、CEA的水平进行检测,同时对比单独检测及联合检测的敏感性与特异性.结果:观察组与对照组相比血清AFP及CEA表达水平较高,差异有统计学意义(P<0.05).血清AFP与CEA联合检测与单独检测AFP或CEA相比敏感性及特异性均较高,差异有统计学意义(P<0.05).结论:肝癌患者肿瘤标志物中血清AFP、CEA的水平可作为诊断肝癌的一项重要参考指标,利用罗式全自动电化学发光分析仪对二者进行联合检测相比于单独检测具有更高的敏感性及特异性.
The Application of the Roche Automatic Electrochemiluminescence Analyzer to Detect Serum AFP and CEA in the Diagnosis of Liver Cancer was Discussed
Objective:To explore and analyze the application of the Roche automatic electrochemiluminescence analyzer to detect serum AFP and CEA in the diagnosis of liver cancer.Methods:Select our hospital from July 2018 to July 2022 cases of liver cancer patients with as an observation group,and choose the same period of 80 cases of healthy adults as a control group,using Roche automatic electrochemiluminescence analyzer for two groups of personnel serum fetoprotein(AFP),carcinogenesis antigen(CEA)level,comparing the sensitivity and specificity of separate detection and combined detection.Results:Compared with the control group,the observation group had higher levels of serum AFP and CEA expression,and the difference was statistically significant(P<0.05).The combined detection of serum AFP and CEA showed higher sensitivity and specificity compared to the individual detection of AFP or CEA,and the difference was statistically significant(P<0.05).Conclusion:The level of serum AFP and CEA in liver cancer patients can be used as an important reference index for the diagnosis of liver cancer.The combined detection has higher sensitivity and specificity than the separate detection.

Roche automatic electrochemiluminescence analyzerAFPCEAdiagnosisliver cancer

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辽阳市中心医院新城医院检验科(辽宁辽阳 111000)

罗式全自动电化学发光分析仪 AFP CEA 诊断 肝癌

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(3)
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