Effect of High-Throughput Dialyzer in Hemodialysis Treatment for End-Stage Renal Disease
Objective:To evaluate the effect of high throughput dialyzer in hemodialysis treatment of end-stage renal disease(ESRD).Methods:From January to October 2022,92 ESRD patients receiving hemodialysis treatment in our hospital were selected as research objects,and were divided into the reference group and the study group by computer random number table method,with 46 cases in each group.The reference group received conventional dialysis treatment,and the study group received high-throughput dialysis treatment with high-throughput dialyzer.Renal function,inflammatory and metabolic indexes and quality of life were observed in 2 groups.Results:Before treatment,SCr and BUN in 2 groups were similar(P>0.05).After treatment,there was no significant difference in SCr and BUN in the study group(P>0.05).Before treatment,IL-6,hs-CRP,Ca,P and iPTH in 2 groups were similar(P>0.05).After treatment,IL-6,hs-CRP,P and iPTH in the study group were lower than those in the reference group(P<0.05),but Ca levels in the two groups were still similar(P>0.05).Before treatment,SF-36 scores in 2 groups were similar(P>0.05);After treatment,SF-36 scores in the study group were higher than those in the reference group,and the difference was statistically significant(P<0.05).Conclusion:The treatment of ESRD with high-throughput dialyzer is better than conventional dialysis,which can reduce inflammatory mediators,promote the metabolism of P and iPTH,and improve the quality of life of patients.