首页|基于气相色谱-离子迁移谱的呼气分析系统研制

基于气相色谱-离子迁移谱的呼气分析系统研制

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人体呼出气体,特别是肺泡气中包含多种痕量挥发性有机化合物,可反映人体代谢及健康情况.文章针对现场呼气分析的需求,设计呼气采样及气相色谱预分离装置,研制基于气相色谱-离子迁移谱的呼气分析系统,实现了呼出气体中肺泡气的采集和分析.系统对氨的理论检出限为2.04ppb,以咖啡顶空气为例实现其混合成分的快速分析.该系统在呼出气体现场分析方面具有较好的应用前景.
Development of a Breath Analysis System Based on Gas Chromatography-Ion Mobility Spectrometry
The exhaled human breath,especially alveolar air,contains a variety of trace volatile organic compounds(VOCs),which can reflect the metabolism and health of the human body.In this paper,a breath sampler and gas chromatography(GC)pre-separate device were designed and a breath analysis system based on gas chromatography-ion mobility spectrometry(GC-IMS)was developed to meet the needs of on-line exhalation analysis.The collection and analysis of alveolar air in exhaled breath was realized.The theoretical detection limit for ammonia is 2.04 ppb.To verify the performance of the device,mixed components of coffee headspace gas were analyzed.The results show that it has a good application prospect in breath analysis.

breath analysissamplingpre-separationgas chromatography-ion mobility spectrometry

吴良杰、贾建、何秀丽、高晓光

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中国科学院空天信息创新研究院传感技术国家重点实验室(北京 100190)

中国科学院大学电子电气与通信工程学院(北京 100049)

呼气分析 采样 预分离 气相色谱-离子迁移谱

国家自然科学基金国家自然科学基金国家自然科学基金

620310226207145361871364

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(5)
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