首页|窄带光成像放大内镜联合卢戈氏碘染色试验在食管早癌浸润深度预测中的应用研究

窄带光成像放大内镜联合卢戈氏碘染色试验在食管早癌浸润深度预测中的应用研究

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目的:分析窄带光成像放大内镜(NBI-ME)联合卢戈氏碘染色试验(LCE)在食管早癌浸润深度预测中的应用.方法:回顾性分析2019年1月~2022年10月在本院收治的疑似食管早癌并行ESD治疗的患者共58例,分别采用NBI-ME(n=26)和NBI-ME联合LCE(n=32)检查.以病理检查的结果作为检验的标准,使用Kappa(K值)一致性分析NBI-ME联合LCE检查对食管早癌以及浸润深度的临床诊断应用价值.结果:NBI-ME联合LCE的检出率明显高于单纯NBI-ME检查(90.63%vs 69.23%),P<0.05.以病理检查结果作为参照的标准,NBI-ME、NBI-ME联合LCE预测浸润深度的准确率各为83.33%、89.66%,敏感度各为86.67%、91.67%,特异度各为66.67%、80.00%,Kappa值各为0.471、0.664.结论:NBI-ME与LCE联合应用于食管早癌的诊断与浸润深度的预测有一定的价值.
Application of Narrow Band Imaging Amplified Endoscopy Combined with Lugo's Iodine Staining Test in Predicting the Depth of Infiltration of Early Esophageal Cancer
Objective:To analyze the application of narrowband imaging magnifying endoscopy(NBI-ME)combined with Lugo's iodine staining test(LCE)in predicting the depth of invasion of early esophageal cancer.Methods:A retrospective analysis was conducted on 58 patients with suspected early esophageal cancer who underwent ESD treatment in our hospital from January 2019 to October 2022.NBI-ME(n=26)and NBI-ME combined with LCE(n=32)were used for examination,respectively.The clinical diagnostic value of NBI-ME combined with LCE examination for early esophageal cancer and depth of invasion was analyzed using Kappa(K-value)consistency analysis based on the results of pathological examination as the test standard.Results:The detection rate of NBI-ME combined with LCE was significantly higher than that of NBI-ME alone(90.63%vs 69.23%)(P<0.05).Using the results of pathological examination as a reference standard,the accuracy of NBI-ME and NBI-ME combined with LCE in predicting infiltration depth were 83.33%and 89.66%,respectively,with sensitivity of 86.67%and 91.67%,specificity of 66.67%and 80.00%,and Kappa values of 0.471 and 0.664,respectively.Conclusion:The combination of NBI-ME and LCE has certain value in the diagnosis and prediction of invasion depth of early esophageal cancer.

narrow band imaging magnifying endoscopyLugo's iodine staining testearly esophageal cancerinfiltration depth

刘炎、陆晶、赖文斌

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福建医科大学附属闽东医院消化内科 (福建 福安 355000)

窄带光成像放大内镜 卢戈氏碘染色试验 食管早癌 浸润深度

宁德市医技提升科研项目

2020005

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(6)
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