Assessment and Prognosis of Impaired Cardiac Function in Diabetes Mellitus with Hyperuricemia by Metabolic Indices Combined with Cardiac Color Ultrasound
Objective:To explore and analyze the evaluation and prognosis of cardiac function impairment in diabetes patients with hyperuricemia by automatic biochemical analyzer combined with cardiac color ultrasound.Methods:50 patients with diabetes accompanied by hyperuricemia,50 patients with simple type 2 diabetes,50 patients with simple hyperuricemia,and 50 healthy people admitted to the hospital from January 2021 to October 2022 were selected as the research objects.They were divided into disease combination group,diabetes group,hyperuricemia group,and health examination group.All four groups provided complete clinical data,All patients completed automatic biochemical instrument testing and cardiac ultrasound testing with knowledge of the examination items,summarized relevant information and examination results of four groups of patients,and conducted statistical analysis.Results:The LDL-C,TG,SCR,BUN,UA in the disease combination group were significantly higher than those in the diabetes group,hyperuricemia group,and health examination group(P<0.05);There was no significant difference in FPG and HbA1c between the disease complicated group and the diabetes group(P>0.05);There was no significant difference in HDL-C,ALT and AST among disease combination group,diabetes group,hyperuricemia group and health examination group(P>0.05);There was no significant difference in TC among the disease combination group,diabetes group and hyperuricemia group(P>0.05);The FPG,HbA1c,LDL-C,TG,TC,SCr,BUN,and UA of the hyperuricemia group were higher than those of the healthy physical examination group,and the differences were statistically significant(P<0.05);TG and UA in hyperuricemia group were significantly higher than those in diabetes group(P<0.05);FPG,HbA1c,LDL-C,TG,TC,SCR,BUN,UA in the health examination group were lower than those in the disease combination group,diabetes group,and hyperuricemia group,with a statistically significant difference(P<0.05).IVST,PWTD,LVM,LVMI,RWT in the disease combination group were significantly higher than those in the diabetes group,hyperuricemia group,and health examination group(P<0.05);LVEF and LVEDD in the disease complicated group were not significantly different from those in the diabetes group(P>0.05);There was no significant difference in IVST,LVEDD,PWTD,LVM,LVMI,RWT between the diabetes group and the hyperuricemia group(P>0.05);IVST,LVEF,LVEDD,PWTD,LVM,LVMI,RWT in the health examination group were lower than those in the disease combination group,diabetes group,and hyperuricemia group,with a statistically significant difference(P<0.05).The positive detection rate of automatic biochemical indicator,positive detection rate of cardiac color ultrasound,and positive detection rate of automatic biochemical indicator+cardiac color ultrasound in the disease combination group were significantly higher than those in the diabetes group,hyperuricemia group,and health examination group(P<0.05).The incidence of complications in the disease combination group was higher than that in the diabetes group,hyperuricemia group,and health examination group,with a statistically significant difference(P<0.05).Conclusion:Automatic biochemical detection and cardiac ultrasound detection in patients with diabetes complicated with hyperuricemia are conducive to early detection of cardiac dysfunction and prediction of complications in patients.
diabetes mellitus with hyperuricemiaphysical examinationautomatic biochemistrycardiac ultrasoundimpaired cardiac functionprognosis