Comparison of Clinical Effect of High Flow Oxygen Inhalation and Sequential Ventilator in the Treatment of Respiratory Failure and its Influence on Serum Inflammatory Factors
Objective:To analyze the clinical effect of high flow oxygen inhalation and sequential ventilator therapy on respiratory failure and its influence on serum inflammatory factors.Methods:93 patients with respiratory failure admitted to our hospital from March 2020 to February 2021 were observed.According to the random number table method,46 cases were divided into an oxygen inhalation group and 47 cases into a breathing group.The oxygen inhalation group received high-flow oxygen therapy,while the respiratory unit received sequential ventilator treatment with a ventilator.Analyze the differences in blood gas analysis indicators,heart rate,respiratory rate,and serum inflammatory factors between the two groups before and after treatment.Results:There was no statistically significant difference in the total effective rate between the oxygen inhalation group and the respiratory unit(P>0.05).After treatment,the PaO2 and blood oxygen saturation of the oxygen inhalation group were higher than those of the respiratory unit,while the heart rate of the oxygen inhalation group was lower than that of the respiratory unit,and the respiratory rate was higher than that of the respiratory unit(P<0.05).After treatment,the serum levels of IL-6,IL-1β and IL-8 in oxygen inhalation group were lower than those in respiratory group(P<0.05).Conclusion:High flow oxygen inhalation and sequential ventilator treatment for respiratory failure have no significant difference in improving heart rate and respiratory rate,but are superior to sequential ventilator treatment in improving blood gas indicators and inflammatory cytokines.
high flow oxygen inhalationhumidifier assisted ventilationrespiratory failure
维普
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