首页|支气管镜下肺泡灌洗对支气管扩张伴感染患者炎症反应及血气分析的影响

支气管镜下肺泡灌洗对支气管扩张伴感染患者炎症反应及血气分析的影响

Effect of Bronchoscopic Alveolar Lavage on Inflammation and Blood Gas Analysis in Patients with Bronchiectasis and Infection

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目的:探究支气管镜下肺泡灌洗对支气管扩张伴感染患者炎症反应及血气分析的影响.方法:选取2021年5月~2022年5月本院收治的60例支气管扩张伴感染患者为研究对象,按照随机数字表法分为两组.对照组(n=30)给予常规治疗,观察组(n=30)给予支气管镜下肺泡灌洗治疗.连续治疗4周.对比两组患者的恢复情况、炎症反应相关指标以及并发症.结果:治疗4周后,观察组的肺部啰音改善时间、发烧改善时间、咳嗽改善时间、住院时间均短于对照组,有统计学差异(P<0.05);观察组的降钙素原(PCT)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平均低于对照组,有统计学差异(P<0.05);观察组并发症总发生率与对照组相当,无统计学差异(P>0.05).结论:支气管镜下肺泡灌洗治疗支气管扩张伴感染可有效缩短症状改善时间及住院时间,有助于提高支气管扩张伴感染患者肺功能,降低机体内炎症反应指标,且不增加并发症发生率,安全性相对较高.
Objective:To investigate the effect of bronchoscopic alveolar lavage on inflammation and blood gas analysis in patients with bronchiectasis and infection.Methods:60 patients with bronchiectasis and infection admitted to our hospital from May 2021 to May 2022 were selected as the study objects and divided into two groups according to random number table method.The control group(n=30 cases)was given conventional treatment,and the observation group(n=30 cases)was given bronchoscopic alveolar lavage.Continuous treatment for 4 weeks.The recovery and inflammatory response related indexes were compared between the two groups.Results:After 4 weeks of treatment,the improvement time of lung rales,fever,cough and hospital stay in the observation group were shorter than those in the control group,with statistical differences(P<0.05).The levels of procalcitonin(PCT),C-reactive protein(CRP)and tumor necrosis factor-α(TNF-α)in observation group were lower than those in control group,with statistical difference(P<0.05).The total incidence of complications in the observation group was similar to that in the control group,with no statistical difference(P>0.05).Conclusion:Bronchoscopic alveolar lavage can effectively shorten the time of symptom improvement and hospital stay in patients with bronchiectasis and infection,and help to improve lung function and reduce the indicators of inflammation in the body.

bronchiectasisto be infectedinflammatory responsebronchoscopic alveolar lavagerecovery situationcomplication

邹来武

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福建省南平市浦城县医院呼吸与危重症医学科(福建 南平 353400)

支气管扩张 感染 炎症反应 支气管镜下肺泡灌洗 恢复情况 并发症

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(8)
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