Analysis of the Effectiveness and Complications of Non-Invasive Ventilation in the Treatment of COPD Complicated with Respiratory Failure
Objective:To review the effect of non-invasive ventilator on chronic obstructive pulmonary disease(COPD)complicated with hypercapnia and its effect on complications.Methods:From April 2023 to March 2024,80 patients with COPD combined with hypercapnia were divided into groups according to their treatment methods.40 patients were treated with symptomatic treatment plan as the reference group,and 40 patients were treated with symptomatic treatment plan plus non-invasive ventilator as the observation group.Pulmonary ventilation function,blood gas index and complications were observed.Results:The pulmonary ventilation function indexes of COPD patients with respiratory failure were similar before treatment,and the indexes of FEV1,FVC and FEV1/FVC increased after treatment,compared with before and after treatment(P<0.05).The indexes of FEV1,FVC and FEV1/FVC in the observation group were higher than those in the reference group(P<0.05),with statistical difference;The blood gas indexes of COPD patients with hypercapnia were similar before treatment,while pH,SaO2 and PaO2 indexes increased and PaCO2 indexes decreased after treatment(P<0.05).The pH,SaO2 and PaO2 indexes in the observation group were higher than those in the reference group(P<0.05),and the PaCO2 indexes were lower than those in the reference group(P<0.01),with statistically significant differences.During the treatment period,there were 2 cases of secondary severe pneumonia in the control group,with an incidence rate of 5.0%.In the observation group,there was 1 case of secondary ventilator-associated pneumonia during the treatment period,with an incidence rate of 2.50%.There was no significant difference between the two groups(P>0.05).Conclusion:Non-invasive ventilator can effectively improve pulmonary ventilation index in COPD patients with hypercapnia,and the short-term effect is significant.
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