Application Analysis of Real-Time Ultrasound Shear Wave Elastography in the Diagnosis of Liver Fibrosis in Schistosomiasis
Objective:To explore and analyze the application effect and value of real-time ultrasound shear wave elastography in the diagnosis of liver fibrosis in schistosomiasis.Methods:A total of 100 patients with liver fibrosis caused by schistosomiasis who were admitted to our hospital between January 2022 and March 2023 were selected as the observation subjects.Liver tissue biopsies were performed and divided into groups based on fibrosis staging criteria,with S0=26,S1=22,S2=15,S3=18,and S4=19.All five groups of patients underwent real-time shear wave elastography using ultrasound.The elastic modulus,relevant serum liver fibrosis indicators,and diagnostic efficacy of the five groups of patients were observed and compared.Results:① After examination,it was found that compared to patients in stage S0,patients in stages S1,S2,S3,and S4 all had higher elastic moduli,and the data comparison was statistically significant(P<0.05);② In the comparison of serum liver fibrosis indicators,the levels of laminin and hyaluronic acid were higher in patients in stages S1,S2,S3,and S4 compared to patients in stage S0,and the data comparison was statistically significant(P<0.05);Compared to patients in stage S0,patients in stages S1,S2,S3,and S4 had higher levels of type Ⅳ collagen and type Ⅲ procollagen,but the data comparison was not statistically significant(P>0.05);③ The diagnostic efficacy of liver parenchymal elastic modulus for different stages of liver fibrosis varies,with the highest diagnostic efficacy observed in stages S1-S4,with thresholds and AUC of 6.80kPa and 0.939,respectively.Conclusion:Real time shear wave elastography using ultrasound has a significant diagnostic effect on liver fibrosis in schistosomiasis,which helps to clarify pathological staging and provides accurate diagnostic basis for later treatment.It is a diagnostic method with high application value.
schistosomiasisliver fibrosisreal time ultrasound shear wave elastographydiagnostic value
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