Objective:To explore the clinical effects of intensity modulated radiation therapy on nasopharyngeal carcinoma patients.Methods:84 cases of nasopharyngeal carcinoma in our hospital from June 2021 to June 2023 were selected and randomly divided into a control group(n=42)and an observation group(n=42)using a random number table method.The control group received two-dimensional radiation therapy,while the observation group received intensity modulated radiation therapy.The clinical effects were compared.Results:The incidence of radiotherapy side effects in the control group and observation group was 35.71%and 14.29%,respectively,with the observation group significantly lower than the control group(P<0.05);The clinical treatment effectiveness rate of the observation group was significantly higher than that of the control group(83.33%,64.29%,P<0.05);After treatment,the observation group showed a significant advantage in improving immune function compared to the control group(P<0.05);After treatment,based on the evaluation results of the control group,the levels of tumor markers in the observation group were significantly lower(P<0.05).Conclusion:Intensity modulated radiation therapy is more effective and safe for nasopharyngeal carcinoma patients,and has a definite effect on improving immune function and reducing serum tumor marker levels.