首页|药物洗脱支架与药物涂层球囊治疗急性冠状动脉综合征患者的临床效果

药物洗脱支架与药物涂层球囊治疗急性冠状动脉综合征患者的临床效果

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目的:观察并比较药物涂层球囊与药物洗脱支架在急性冠状动脉综合征患者中的临床治疗效果.方法:选取2020年1月~2023年1月在漳州市长泰区陈巷镇中心卫生院诊治的40例急性冠状动脉综合征患者为研究对象.根据采取的介入治疗方法不同将40例患者分为不同的组别,其中20例采取药物涂层球囊介入治疗的患者作为涂层球囊组,20例采用药物洗脱支架介入治疗的患者作为洗脱支架组.观察并比较两组患者介入治疗前后冠状动脉病变处最小管腔直径、管腔狭窄率、术后6个月冠状动脉病变处最小管腔直径和晚期管腔丢失.结果:与介入治疗前比较,治疗后两组患者的后冠状动脉病变处最小管腔直径均明显更大(P<0.05),管腔狭窄率均明显更低(P<0.05);与涂层球囊组比较,洗脱支架组的后冠状动脉病变处最小管腔直径无明显差异(P>0.05),管腔狭窄率明显更低(P<0.05);治疗6个月后,两组后冠状动脉病变处最小管腔直径无明显差异(P>0.05),洗脱支架组晚期管腔丢失明显高于涂层球囊组(P<0.05).结论:药物洗脱支架与药物涂层球囊在急性冠状动脉综合征患者中均具有临床疗效,且药物涂层球囊在降低患者术后晚期管腔丢失中的优势更明显.
Clinical Effect of Drug-Eluting Stents with Drug-Coated Balloons in Patients with Acute Coronary Syndrome
Objective:To observe and compare the clinical therapeutic effect of drug-coated balloons and drug-eluting stents in patients with acute coronary syndrome.Methods:A total of 40 patients with acute coronary syndrome were diagnosed and treated in the Zhangzhou Changtai District Chenxiang Town Central Health Center and the period from January 2020 to January 2023 was enrolled.According to the different interventional methods used,40 patients were divided into different groups,of which 20 patients who underwent drug-coated balloon intervention were used as the coated balloon group and 20 patients who underwent drug-eluting stent intervention were used as the eluting stent group.The minimum diameter of the official cavity,the rate of stenosis,the diameter of the minimum lumen and the late cavity loss of coronary artery lesions 6 months after surgery were observed and compared between the two groups.Results:Compared with the pre-interventional treatment,the minimum cavity diameter of posterior coronary artery lesion was significantly larger(P<0.05)and the stenosis rate of official cavity was significantly lower(P<0.05)in the two groups after treatment,compared with drug-coated balloons,there was no significant difference in the minimum cavity diameter(P>0.05)and lower stenosis rate(P<0.05)and 6 months after treatment,there was no significant difference in the minimum cavity diameter of coronary artery lesion(P>0.05)between the two groups.The late official cavity loss in the eluting stent group was significantly higher than that in the coated balloon group(P<0.05).Conclusion:Both drug-eluting stents and drug-coated balloons have clinical efficacy in patients with acute coronary syndrome,and drug-coated balloons have more obvious advantages in reducing the loss of official cavity in patients with late postoperative period.

acute coronary syndromedrug-eluting stentsdrug-coated balloonsclinical efficacy

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漳州市长泰区陈巷镇中心卫生院药房 (福建 漳州 363901)

急性冠状动脉综合征 药物洗脱支架 药物涂层球囊 临床疗效

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(16)