首页|3.0T西门子磁共振检查在急性脑梗死溶栓后血管再通预测应用分析

3.0T西门子磁共振检查在急性脑梗死溶栓后血管再通预测应用分析

Application of 3.0T Siemens Magnetic Resonance Examination in the Prediction of Vascular Recanalization After Thrombolysis in Acute Cerebral Infarction

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  • NETL
  • NSTL
  • 万方数据
目的:分析3.0T西门子磁共振检查在急性脑梗死溶栓后血管再通预测应用.方法:选取本院2022年5月～2023年5月收诊的74例急性脑梗死患者,均接受静脉溶栓治疗,根据血管再通情况分为再通组和未再通组;90d修正Rankin量表(mRS)评分分为预后良好组和预后不良组,比较各组患者功能性磁共振成像(fMRI)参数,并使用受试者工作特征曲线(ROC)评价fMRI参数的预测效能.结果:再通组梗死核心区rCBV、缺血半暗带MTT以及梗死核心区ADC均低于未再通组,再通组的SMC区激活率高于未再通组(P<0.05);预后良好组的梗死核心区rCBV、缺血半暗带MTT、梗死核心区ADC均比预后不良组低,SMC区激活率高于预后不良组(P<0.05);74例患者中,有41例(55.41%)患者在静脉溶栓后血管再通;12例患者再静脉溶栓治疗后,血流TICI达1级,占16.22%.在溶栓后90d,有44例(59.46%)患者mRS评分0～2分,其预后良好率为59.46%.结局为血管再通的灵敏度、特异性、准确率、阳性预测值、阴性预测值分别为:83.87%、77.62%、80.79%、82.75%、81.52%.结局为预后不良的灵敏度、特异性、准确率、阳性预测值、阴性预测值分别为:89.91%、84.61%、86.92%、88.13%、88.68%.结论:3.0T西门子磁共振检查在急性脑梗死溶栓后血管再通预测中具有较高的效能,可为临床提供参考.
Objective:To analyze the application of 3.0T Siemens magnetic resonance examination in predicting vascular recanalization after thrombolysis in acute cerebral infarction.Methods:74 patients with acute cerebral infarction admitted to our hospital from May 2022 to May 2023 were selected,all of whom received intravenous thrombolysis and were divided into recanalization group and non-recanalization group according to their vascular recanalization.The 90-day modified Rankin scale(mRS)score was divided into good prognosis group and poor prognosis group.fMRI parameters of each group were compared,and the predictive efficacy of fMRI parameters was evaluated using receiver operating characteristic curve(ROC).Results:rCBV,MTT of ischemic penumbra and ADC of infarction core in recirculation group were lower than those in no recirculation group,and the activation rate of SMC region in recirculation group was higher than that in no recirculation group(P<0.05).The rCBV,MTT and ADC of infarction core in good prognosis group were lower than those in poor prognosis group,and the activation rate of SMC region was higher than that in poor prognosis group(P<0.05).Among the 74 patients,41 cases,accounting for 55.41%,were revascularized after intravenous thrombolysis;There were 12 patients,accounting for 16.22%,whose blood flow TICI grade reached grade 1 after intravenous thrombolysis.At 90 days after thrombolysis,there were 44 cases,accounting for 59.46%of the patients with mRS scores between 0-2,and the good prognosis rate was 59.46%.The results showed that the sensitivity,specificity,accuracy,positive predictive value and negative predictive value of vascular recanalization were 83.87%,77.62%,80.79%,82.75%and 81.52%,respectively.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of the outcome with poor prognosis were 89.91%,84.61%,86.92%,88.13%and 88.68%,respectively.Conclusion:3.0T Siemens magnetic resonance examination has a high efficacy in the prediction of vascular recanalization after thrombolysis in acute cerebral infarction,and can provide clinical reference.

3.0T Siemens magnetic resonanceacute cerebral infarctionintravenous thrombolysisvascular recanalizationforecast

刘瑞光、李婧

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昌乐县人民医院急诊卒中科 (山东 潍坊 262400)

昌乐齐城中医院脑病一科 (山东 潍坊 262400)

3.0T西门子磁共振 急性脑梗死 静脉溶栓 血管再通 预测

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子：0.375
ISSN：1006-6586
年,卷(期)：2024.30(18)