The Application of an Innovative Component in Pathological Embedding Process of Fragment Breast Tissue by Mammotome
Objective:To explore the application value of an innovative component in pathological embedding link of breast Mammotome fragmented tissue.Methods:60 specimens of fragmented breast tissues by Mammotome from January 2024 to May 2024 were collected.2 fragmented tissues were taken from each case and randomly divided into two groups.All of them were dehydrated according to the routine pathological procedures and then embedded.Embedding tweezers group:Conventional embedding treatment using embedding tweezers;Innovative component group:Used toothless tweezers to adjust the position of some broken tissues so as not to overlap each other,used preheated metal blocks of innovative components instead of embedding tweezers to lightly crush the tissues,so as to concentrate the fragmented tissues at the bottom of the embedding mold,covered the embedding box,and then placed the embedding mold with broken tissues in the square tray of innovative components for cooling,and the rest embedding methods were the same as those of the embedding tweezers group.The embedding time and qualified rate of different embedding methods were compared,and the rough repair thickness and broken tissue damage of wax blocks under different embedding methods were compared.Results:The average embedding time of each fragmented tissue in the embedding tweezers group was(25.68±4.16)s,which was significantly longer than that in the innovative component group(t=13.21,P<0.001);The qualification rate of embedding tweezers group was 88.33%(53/60),which was lower than that of innovative component group(100.00%,60/60)(χ2=5.46,P<0.05);The average rough thickness of each wax block in the embedding tweezers group was(529.00±50.01)μm,which was significantly thicker than that in the innovative component group(370.00±55.42)μm(t=16.50,P<0.001);The tissue injury rate of the embedding tweezers group was 18.33%(11/60),which was significantly higher than that of the innovative component group[0(0/60)](χ2=12.11,P<0.01).Conclusion:Using innovative components to optimize the pathological embedding process of breast Mammotome fragment tissue has high embedding efficiency and qualified rate,less rough repair and less damage to fragment tissue during slicing,which can improve the work efficiency and slice quality.