Dosimetry Differences in Volumetric Volumetric Intensity Modulated Arc Therapy Schedules Using Three Different Flux Smoothing Systems in the Monaco Planning System for Patients After Rectal Cancer
Objective:To analyze the dosimetric differences of the patients in the Monaco planning system.Methods:25 rectal cancer patients admitted to the hospital from January 2020 to January 2021 were selected for the same optimization conditions,three(Volumetric Intensity Modulated Arc Therapy,VMAT)plans,namely FSL,FSM and FSH,and then dose verified using Matrixx two-dimensional flat panel detector.The dose-volume parameters of target and organ at risk(OAR)were evaluated,and the differences between γ pass rate(GRP),tract out time(T),CP,MU,GI,HI,and CI were compared.Results:Compared with the FSH and FSM groups,lower HI levels in the FSL group,the higher level of CI,differdifference between groups(P＜0.05);Higher GI levels in the FSL and FSM groups than in the FSH group(P＜0.05).However,the comparison of GI levels in the two groups was not statistically significant(P＜0.05);The FSM and FSL groups showed obvious advantages in D98%and Dmin improvement of PTV,compared with the FSH group was significant(P＜0.05);Bladder Dmean,V40 and V30 were higher in FSH group and FSM group than in FSL group(P＜0.05);In the protection of the left femoral head,the FSM group and the FSL group were significantly better than the FSH group(P＜0.05).However,there was no statistical difference in the intestinal protection index among the three groups(P＞0.05);At the same time,at the 3%/3mm standard,all 3 groups planned GRP was higher than 99%,in accordance with the clinical requirements.However,under the 2%/2mm and 1%/1mm standards,GRP in the FSM and FSH groups,and higher than those in the FSL group,the difference were significant(P＜0.05).Conclusion:Clinically,the GRP and dosimetry parameters of FSL,FSM and FSH 3 could meet the clinical requirements,but compared with FSH and FSM,FSL could improve the plan quality.FSM and FSH were significantly better than that of FSL.Therefore,in clinical treatment,the individual differences of patients should be fully considered,and then combined with clinical requirements to choose an appropriate radiotherapy plan,in which FSM is characterized by high planned execution efficiency and plan quality,which can be used as a preferred treatment method.
万方数据
维普
