首页|早期消化道癌患者内镜下黏膜剥离术对患者复发情况的影响

早期消化道癌患者内镜下黏膜剥离术对患者复发情况的影响

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目的:探讨早期消化道癌患者内镜下黏膜剥离术对患者复发情况的影响.方法:从2019年1月~2020年12月晋江市医院收治的早期消化道癌患者中选取108例纳入本次研究,应用随机数字表法将其均分为两组,其中采用内镜下黏膜切除术治疗的为对照组(54例),采用内镜下黏膜剥离术的为观察组(54例),对治疗后两组患者的病灶切除率、术后复发率进行观察,同时对比两组术后1年、3年生存率及术后半年生活质量水平.结果:相较于对照组,观察组病灶整体切除率和治愈性切除率均明显更高,组间差异显著(P<0.05);相较于对照组,观察组术后复发率明显更低,复发时间明显延长,且主要是异时性复发,组间差异显著(P<0.05);相较于对照组,观察组术后半年生活质量各维度指标明显更高,组间差异显著(P<0.05).结论:早期消化道癌患者采用内镜下黏膜剥离术治疗,有助于提升内镜下组织学疗效,使得患者术后复发风险得以降低,复发期得到延长,显著提高了患者的术后生活质量,为早期消化道癌患者提供了更为可靠的治疗选择.
The Impact of Endoscopic Mucosal Dissection on the Recurrence of Early Gastrointestinal Cancer Patients
Objective:To investigate the effect of endoscopic mucosal dissection on the recurrence of early gastrointestinal cancer patients.Methods:108 patients with early gastrointestinal cancer admitted to Jinjiang Hospital from January 2019 to December 2020 were selected for this study.They were randomly divided into two groups using a random number table method.The control group(54 cases)received endoscopic mucosal resection,while the observation group(54 cases)received endoscopic mucosal dissection.The lesion resection rate and postoperative recurrence rate of the two groups were observed after treatment,and the 1-year and 3-year survival rates,as well as the quality of life level in the first half of the year after surgery,were compared between the two groups.Results:Compared with the control group,the overall resection rate and curative resection rate of the observation group were significantly higher,and the difference between the groups was significant(P<0.05);Compared with the control group,the observation group had a significantly lower postoperative recurrence rate,a significantly prolonged recurrence time,and mainly metachronous recurrence,with significant differences between the groups(P<0.05);Compared with the control group,the observation group showed significantly higher quality of life indicators in all dimensions six months after surgery,with significant differences between the groups(P<0.05).Conclusion:Endoscopic mucosal dissection treatment for early gastrointestinal cancer patients can improve the histological efficacy under endoscopy,reduce the risk of postoperative recurrence,prolong the recurrence period,significantly improve the postoperative quality of life,and provide a more reliable treatment option for early gastrointestinal cancer patients.

early digestive tract cancerendoscopic mucosal dissectionrecrudescence

黄邦宏、陈梅香

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晋江市医院消化内科(福建 泉州 362000)

早期消化道癌 内镜下黏膜剥离术 复发

2024

中国医疗器械信息
中国医疗器械行业协会

中国医疗器械信息

影响因子:0.375
ISSN:1006-6586
年,卷(期):2024.30(19)