The Value of Optical Coherence Tomography Combined with 20MHz High-Frequency Ultrasound in the Diagnosis of Age-Related Macular Degeneration
Objective:To investigate the application value of optical coherence tomography (OCT) combined with 20MHz high-frequency ultrasound in the diagnosis of age-related macular degeneration (AMD). Methods:70 patients treated from October 2022 to October 2023 were selected as the study subjects,with the pathological diagnosis as the "gold standard",there were 65 cases diagnosed of age-related macular degeneration,with optical coherence tomography and 20MHz high frequency ultrasound alone and in combination in these 65 patients,compare the accuracy of the individual diagnosis and the combined diagnosis. Results:Among the 65 patients,57 were diagnosed using optical coherence tomography,with an accuracy rate of 87.69％,and 2 were missed,with a missed diagnosis rate of 12.31％;54 cases were diagnosed using 20MHz high-frequency ultrasound,with an accuracy rate of 83.08％. 9 cases were missed,with a missed diagnosis rate of 13.85％,and 2 cases were misdiagnosed,with a misdiagnosis rate of 3.08％;63 cases were diagnosed using optical coherence tomography combined with 20MHz high-frequency ultrasound,with an accuracy rate of 96.92％. 2 cases were missed,with a missed diagnosis rate of 3.08％. The diagnostic accuracy of optical coherence tomography combined with 20MHz high-frequency ultrasound was significantly higher than that of the two methods alone (P<0.05);The sensitivity and specificity of optical coherence tomography were 96.61％ and 27.27％,respectively. The sensitivity and specificity of 20MHz high-frequency ultrasound examination were 94.73％ and 15.38％,respectively. The sensitivity and specificity of optical coherence tomography combined with 20MHz high-frequency ultrasound examination were 98.44％ and 66.67％,respectively. Conclusion:OCT and 20MHz can be effectively used in the diagnosis of age-related macular degeneration,with OCT has higher accuracy and reliability in the imaging and analysis of the macular area,which provides strong support for the early diagnosis of AMD.
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