The Diagnostic Value and Related Parameter Analysis of High-Frequency Ultrasound Combined with Ultrasound Elastography for Papillary Thyroid Carcinoma
Objective:To analyze the efficacy of high-frequency ultrasound combined with ultrasound elastography in the diagnosis of papillary thyroid carcinoma (PTC). Methods:80 suspected PTC patients were admitted to Putian First Hospital from June 2021 to December 2023,all of whom received high-frequency ultrasound and ultrasound elastography diagnosis. Pathological examination was used as the "gold standard" to analyze the efficacy of the two measures alone or in combination for diagnosis. Results:Among the 80 patients,pathological examination detected a total of 59 cases of PTC,high-frequency ultrasound detected 48 cases,ultrasound elastography detected 50 cases,and combined detection of 58 cases;Using pathological examination as the "gold standard",the sensitivity and accuracy of high-frequency ultrasound combined with ultrasound elastography in diagnosing PTC were 96.61％ (57/59),98.75％(79/80),and the negative predictive value was 90.91％ (20/22),which was higher than the 79.66％ (47/59),97.92％ (47/48),62.50％ (20/32),81.36％ (48/59),83.75％(67/80),and 63.33％ (19/30) diagnosed separately by both methods (P<0.05);The Kappa test showed that there was excellent consistency between the two combined diagnoses and the "gold standard" (Kappa value=0.905,P=0.000);The proportion of unclear boundaries in PTC patients was 67.80％ (40/59),the proportion of tumor diameter>0.5cm was 69.49％ (41/59),the proportion of posterior attenuation was 57.63％ (34/59),the proportion of insufficient blood supply was 64.41％ (38/59),the proportion of irregular morphology was 84.75％ (50/59),the ultrasound elasticity score (ES) was (3.50±0.49),and the elasticity coefficient (SR) was (3.19±0.46),which was higher than that of non PTC patients. 38.10％ (8/21),23.81％ (5/21),28.57％ (6/21),33.33％ (7/21),42.86％ (9/21),(2.01±0.23),(1.38±0.31) (P<0.05) of the patients. Conclusion:High-frequency ultrasound combined with ultrasound elastography can effectively diagnose PTC,and the examination parameters vary greatly depending on the nature of the disease. The combination of the two has certain diagnostic value.
thyroid papillary carcinomahigh-frequency ultrasoundultrasound elastographysensitivityspecificitynegative predictive value
万方数据
维普
