Effect of Laparoscopic Three-Well Cholecystectomy on Postoperative Body Stress Response and Immune Function in Patients with Acute Calculous Cholecystitis
Objective:To analyze the effectiveness of laparoscopic three port cholecystectomy in the treatment of acute calculous cholecystitis patients. Methods:Sixty patients with acute calculous cholecystitis admitted to our hospital were selected for this clinical practice study. The patient admission period was from January 2022 to January 2024,and they were divided into groups using the single and double number method. 30 patients who were assigned to the single number were included in the control group,and the treatment method was open surgery. 30 patients who were assigned to the double number were included in the observation group,and the treatment method was laparoscopic three hole cholecystectomy. The stress response levels of prostaglandin E2,serum substance P,immune function levels of CD3+,CD4+,and postoperative complications were compared between the two groups of patients before and after surgery. Results:There was no statistically significant difference in stress response levels such as prostaglandin E2 and serum substance P between the two groups of patients before surgery,with P>0.05. After surgery,the observation group was lower than the control group,with P<0.05. There was no statistically significant difference in immune function levels such as CD3+and CD4+between the two groups before surgery,with P>0.05. After surgery,the observation group was higher than the control group,with P<0.05. The incidence of postoperative complications was lower in the observation group than in the control group,with P<0.05. Conclusion:Laparoscopic three hole cholecystectomy has a significant effect on the treatment of acute calculous cholecystitis,which not only reduces the perioperative stress response level of patients,but also improves their immune function,thereby reducing their postoperative complications.
laparoscopic three port cholecystectomyacute calculous cholecystitisstress responseimmunityinfluence
万方数据
维普
