Brain natriuretic peptide in old age chronic heart failure and application of the dynamic change of brain natriuretic & nbsp;peptide the clinical effect of treatment
Objective To explore old age chronic heart failure patients with brain natriuretic peptide changes and lyophilization restructuring the human brain sodium peptide the clinical curative effect of the treatment of heart failure. Methods Select our heart hospitalized elderly chronic heart failure patients(intervention group) and older than chronic heart failure patients(control group) the 81 examples, in the conventional treatment on the basis of, intervention group the lyophilization recombinant human BNP plenty for treatment. Results The intervention group BNP and LVEF comparing with the control group there were significant differences, as the cardiac function classification increases, BNP increase, LVEF down; Before and after treatment of the intervention group BNP, LVEF and heart rate were significantly difference, During follow-up, the intervention group before treatment BNP level higher than the normal range of patients and normal compared to patients with mortality, annual average hospitalization number and the total length of hospital stay all have difference, Above comparative differences were statistically significant(P <0.05). Conclusion Old age chronic heart failure patients with brain natriuretic peptide can not only the dynamic change of reaction cardiac function classification situation, the higher level and the severity of the heart failure was positively related to the process of heart failure is evaluation and prognosis indicator; And the clinical lyophilized recombinant human brain peptide sodium treatment of senile chronic heart failure effect is good.
The oldChronic heart failureBrain natriuretic peptide
NETL
NSTL
万方数据
维普
