Clinical Observation of Shenkang Injection Combined with Haikunshenxi Capsule in the Treatment of Chronic Renal Failure(CRF)
Objective To observe the therapeutic efficacy of Shenkang injection combined with Haikunshenxi capsule in treatment of patients with chronic renal failure. Methods 68 patients with chronic renal failure were randomly divided into treatment group(36 cases) and control group(32 cases). Shenkang injection combined with Haikunshenxi capsule were given based on the routine treatment in treatment group, while Brevis capus Injection was performed in control group. Blood urea nitrogen(BUN), serum creatinine(Scr), β2-microglobulin(β2-M), and cystatinC(CysC) of patients in each group were observed pre and post treatment. Results The therapeutic efficacy of treatment group(effective rate 88.9% ) was better than that of control group(effective rate 68.8%). The decreases of blood urea nitrogen(BUN), serum creatinine(Scr), β2-microglobulin(β2-M), and cystatinC(CysC) in treatment group were significantly more than those in control group(P <0.05). There were no serious ADRs found in two groups. Conclusions Shenkang injection combined with Haikunshenxi capsule not only relieve the clinical symptom of the patients with chronic renal failure, but also improve their renal function with no obvious side-effect and postpone the deterioration of the patients with chronic renal failure.