首页|酚妥拉明与ACEI联用方案治疗婴幼儿重症肺炎合并心力衰竭的临床研究

酚妥拉明与ACEI联用方案治疗婴幼儿重症肺炎合并心力衰竭的临床研究

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目的分析探讨酚妥拉明联合血管紧张素转换酶抑制剂(ACEI)在治疗婴幼儿重症肺炎合并心力衰竭方面的临床效果.方法选取2009年4月-2012年5月间在我院住院治疗的70例重症肺炎合并心力衰竭患儿,将其分为观察组和对照组各35例.对照组采用常规治疗措施,观察组在对照组基础上加用酚妥拉明与血管紧张素转换酶抑制剂卡托普利,比较两组的临床疗效.结果观察组用药24h后总有效率为91.4%,高于对照组的80.0%,组间差异有统计学意义(P <0.05);观察组患儿心衰纠正时间、症状缓解时间、肺部音消失时间以及总的住院时间均明显短于对照组患儿(P <0.05).结论酚妥拉明联合ACEI在治疗婴幼儿重症肺炎合并心力衰竭方面疗效显著,患儿心衰症状改善明显,值得临床推广.
The clinical research of phentolamine associated with ACEI program in the treatment of infants with severe pneumonia & nbsp;complicated by heart failure
Objective To analyze and explore the clinical effect of phentolamine combined with angiotensin-converting enzyme inhibitors(ACEI) in the treatment of infants with severe pneumonia complicated by heart failure. Methods 70 patients with severe pneumonia complicated by heart failure in children hospitalized in our hospital from April 2011 to May 2012 were chosen, and they were divided into the observation group and the control group. The control group of 35 cases was taken with conventional treatment. The observation group of 35 cases was taken with phentolamine and angiotensin-converting enzyme inhibitor captopril on the basis of the control group. The clinical efficacy of the two groups was compared. Results The total effective rate of children with drug treatment after 24h of the observation group was 91.4%, while the total effective rate of the treatment in the control group was 80.0%. The statistics showed that the total efficiency rate in the two groups of patients were with statistically significant differences(P <0.05). The correct time, remission time, pulmonary disappeared time and total hospitalization time for children with heart failure in the observation group was significantly shorter than children in the control group(P <0.05). Conclusion The effect of phentolamine united ACEI in the treatment of infants with severe pneumonia complicated by heart failure is significant, symptoms of children with heart failure improve significantly, and the clinical is worthy of promotion.

Phenol phentolamineAngiotensin-converting enzyme inhibitorsCaptoprilSevere pneumoniaHeart failure

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611130 四川省成都市温江区中医医院儿科

酚妥拉明 血管紧张素转换酶抑制剂 卡托普利 重症肺炎 心力衰竭

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(1)
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