The clinical research of phentolamine associated with ACEI program in the treatment of infants with severe pneumonia & nbsp;complicated by heart failure
Objective To analyze and explore the clinical effect of phentolamine combined with angiotensin-converting enzyme inhibitors(ACEI) in the treatment of infants with severe pneumonia complicated by heart failure. Methods 70 patients with severe pneumonia complicated by heart failure in children hospitalized in our hospital from April 2011 to May 2012 were chosen, and they were divided into the observation group and the control group. The control group of 35 cases was taken with conventional treatment. The observation group of 35 cases was taken with phentolamine and angiotensin-converting enzyme inhibitor captopril on the basis of the control group. The clinical efficacy of the two groups was compared. Results The total effective rate of children with drug treatment after 24h of the observation group was 91.4%, while the total effective rate of the treatment in the control group was 80.0%. The statistics showed that the total efficiency rate in the two groups of patients were with statistically significant differences(P <0.05). The correct time, remission time, pulmonary disappeared time and total hospitalization time for children with heart failure in the observation group was significantly shorter than children in the control group(P <0.05). Conclusion The effect of phentolamine united ACEI in the treatment of infants with severe pneumonia complicated by heart failure is significant, symptoms of children with heart failure improve significantly, and the clinical is worthy of promotion.