TLCS测定加味八珍益母颗粒中盐酸水苏碱的含量
TLCS Determination of stachydrine hydrochloride in Jiawei Bazhenyimu Granules
侯景英 1李志军 1周玉新 2杜树山3
作者信息
- 1. 453400 新乡，河南宏力医院药学部
- 2. 475004 开封，河南大学中药研究所
- 3. 100088 北京，北京师范大学资源学院
- 折叠
摘要
目的建立测定加味八珍益母颗粒中盐酸水苏碱含量.方法采用薄层扫描法测定盐酸水苏碱含量,硅胶G薄层预制板,正丁醇-盐酸-乙酸乙酯(831)溶液为展开剂,测定波长510nm,Sx=3反射式锯齿扫描.结果盐酸水苏碱点样量在4.43-11.07μg间和吸收度积分值呈良好的线性关系,平均回收率为100.08%,RSD=2.49%.结论薄层扫描法便捷、灵敏、准确,可作为加味八珍益母颗粒的质量控制方法.
Abstract
Objectives To establish an accurate method for the determination of stachydrine hydrochloride in Jiawei Bazhenyimu Granules. Method TLC scanner was selected to detect silica gela thin layer. The sample was separated by using n-BuOH-HCl-EtOAC(8 3 1) solution, the plate was scanner at 510nm. Results The linear ranges of stachydrine hydrochloride was 4.43-11.07μg, the average recovery was 100.08% and RSD was 2.49%. Conclusion The method was simple and accurate, and can be used for the quality control of Jiawei Bazhenyimu Granules.
关键词
加味八珍益母颗粒/盐酸水苏碱/薄层扫描法Key words
Jiawei Bazhenyimu Granules/Stachydrine hydrochloride/TLCS引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据