A clinical study of combined Citalopram Hydrobromide and small dose Mirtazapine tablets in the treatment of depression LI
Objective To compare the curative effect of treating and adverse reaction in the treatment for depression between the group take orally Citalopram Hydrobromide tablets with small dose Mirtazapine tablets and the group only take orally Citalopram Hydrobromide tablets. Methods Eighty-eight depression patients were divided into two groups in random, treatment group take orally Citalopram Hydrobromide tablets with small dose Mirtazapine tablets(n=45), control group only take orally Citalopram Hydrobromide tablets(n=43). Course of treatment was six weeks. Adopted Hamilton depression rating scale(HAMD) estimating the curative effect of treating before treatment and 1, 2, 4, 6 weeks for all patients. And adopted Treatment Emergent Symptom Scale(TESS) evaluating adverse reactions for all patients. Results The overall efficacy was significant difference for two groups: the treatment group got effective fast, clinical cure rate was higher, side effects was not significantly increased. Conclusion Takeing orally Citalopram Hydrobromide tablets with small dose Mirtazapine tablets treat depression is worth clinical promoting.
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万方数据
维普
