The observation of the effect for intraperitoneal hyperthermic perfusion combined with systemic intravenous chemotherapy in the application of postoperative gastric
Objective To investigate the clinical effect for intraperitoneal hyperthermic perfusion combined with systemic intravenous chemotherapy in the application of postoperative gastric. Methods The clinical data of 88 patients in our hospital for gastric surgery was taken for retrospective analysis. They were divided into the treatment group and the control group, and 44 cases in each group. The treatment group was treated with intraperitoneal hyperthermic perfusion chemotherapy combined with systemic chemotherapy according to postoperative chemotherapy treatment and control group patients were only taken with intravenous chemotherapy treatment. The survival rate, relapse rate and transfer rate, and incidence of adverse reactions 2 months to 5 years after surgery were compared. Results The survival rate of patients in the treatment group 2 years after the treatment group was slightly higher than that in the control group, but there was no significant difference(P>0.05). The survival rate of the treatment group 3 years and 5 years after surgery were 68.18% and 52.27%, and 56.82% and 38.64% in the control group, there was significant difference, P<0.05. The recurrence rate and metastasis rate in the treatment group was 63.64%, significantly lower than the control group of 77.27%, P<0.05. There was no statistically significant difference for the adverse reactions, P>0.05. Conclusion Intraperitoneal hyperthermic perfusion combined with systemic intravenous chemotherapy for gastric cancer after surgery can significantly improve the survival rate, significantly lower relapse rate and transfer rate of postoperative patients, and with little drug side effects.
NETL
NSTL
万方数据
维普
