The Application Value of Strengthening Measles Vaccine to Block Biphase Displacement for People of Childbearing Age before Pregnancy
Objectives Explore the measles immunity levels before and after strengthening measles vaccine(MV) injection for childbearing age population, and further analyze the impact of the childbearing aged women and men's measles immunization level on measles elimination to provide a scientific basis for the ultimate realization of the measles elimination goal. Methods Select 60 child-bearing aged hospital medical staff ranged from 22 to 35 -year-old and observe the differences in measles immunization levels before and after 26 months of MV injection, also adopt enzyme-linked immune sorbent assay test(ELISA) to detect the IgM and IgG antibodies of serum before and after its MV immunity. Results The χ2 test result before and after the women and men of reproductive age were inoculated: in 1 200 level, χ2=7.32, P<0.05, in 1 800 level, χ2=10.25, P<0.05; there exists statistical differences in measles immunization levels before and after the injection. Conclusion Women and men of reproductive age or couples inoculate MV timely and safely before pregnancy can not only improve the level of measles antibody of childbearing aged people but also can improve the 8 -month-old infants' measles antibody level of fetal transmission of measles before measles vaccine, which is able to effectively reduce the incidence of measles among people over 25 years old and below 8 -month-old infant, so that the effect of ‘one generation immune while two generations benefit' can be achieved. It is significant for blocking biphase displacement.
People of childbearing ageBefore pregnancyMeasles vaccineBiphase displacement