Objectives Previous studies have shown that different contrast volume(CV) is important in generating contrast-induced nephropathy(CIN). The aim of our research was to analyze weather various CV would lead to diverse condition in renal function. Methods A total of 252 patients, with acute cerebrovascular disease, were enrolled. According to their CV, we divided them into two groups, people with CV≤150ml in group A, and CV>151ml in B. Then we can evaluate these patients' renal function through testing their serum Cr(sCr), creatinine clearance rate(cCr), urea nitrogen(BUN), uric acid(UA) and cystatin-C(CysC) level. Results After the digital subtraction angiography(DSA), both of the cCr, BUN and UA in group A and cCr and UA in group B were statistical significance. Moreover, the sCr of 11 people, 3 cases in A and 8 cases in B, have increase by 25% from baseline. Conclusions Contrast medium would have certain influence on renal function. Besides, more volume would increase the morbidity of CIN. However, there was no clear correlation ship between them when the CV ranges from 56ml to 245ml.
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NSTL
万方数据
维普
