Application of 18F-fluorodeoxyglucose positron emission tomography-CT imaging and SCC-Ag in serum for diagnosis of early recurrence or metastasis of Cervical squamous carcinoma
Objective To explore the application of 18F-FDG PET/CT and SCC-Ag in serum check for diagnosis of early recurrence or metastasis of Cervical squamous carcinoma. Methods Choose 46 cervical squamous carcinoma postoperative patients with suspected recurrence or metastasis by order in Shanxi Provincial Tumour Hospital, who received 18F-FDG PET/CT and SCC-Ag in serum check respectively. The patients who confirmed by second surgery or puncture were compared with the pathologic results, the others were combined with follow-up clinic(>6 months) or clinical diagnosis. Results There were 46 cervical squamous carcinoma postoperative patients with suspected recurrence or metastasis, 30 of 46 patients were finally appear recurrence or metastasis, 16 had not; Among 30 patients who were confirmed exist recurrence or metastasis nidus, 18F-FDG PET/CT found 28, 2 fasle negative;meanwhile,18 of 30 patients' level of SCC-Ag in serum were rose, 12 fasle negative; Among 16 patients who were not confirmed exist recurrence or metastasis nidus, 18F-FDG PET/CT found 1 fasle positive;meanwhile, 15 of 16 patients' level of SCC-Ag in serum were in norma rangel, 1 fasle positive. Conclusions Both 18F-FDG PET/CT scan and SCC-Ag in serum check is effective method to detect recurrence or metastasis of Cervical squamous carcinoma postoperative patients, but the SCC-Ag levels in serum check had a higher false negative rate than 18F-FDG PET/CT scan; Cervical squamous carcinoma postoperative patients should accept 18F-FDG PET/CT examination regularly, especially the patients whose level of SCC-Ag in serum rise.
NETL
NSTL
万方数据
维普
