Application of arsenic trioxide in the treatment of cancer
Arsenic trioxid is a major component of the traditional Chinese medicine of arsenic, which was used as a drug has a history of over two thousand years, the initial application is the treatment of syphilis, tuberculosis and so on. From the nineteen seventies in the treatment of refractory and relapsed acute promyelocytic leukemia(APL) has good effect, Arsenic's medicinal value began to receive people's attention, At the beginning of this century, U.S. Food and Drug Administration allowed arsenic trioxide to acute promyelocytic leukemia, multiple myeloma and myelodysplastic syndrome.From then on, there was a stirring of interest in antitumor effection and mechanism of arsenic trioxid in domestic and foreign. And a number of experiments has been conducted arounding it.In this paper, the research progress in anti-tumor were reviewed.